No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
|
1. Apply sex-specific ruleNone |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
Extra metadata
Similar endpoints
↥List of similar endpoints to Mental retardation based on the number of shared cases.
Similar with more cases:
- Mental retardation
- Mental retardation
- Psychiatric diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 42454 | 18381 | 23958 |
Only index persons | 34472 | 15015 | 19457 |
Unadjusted period prevalence (%) | |||
Whole population | 0.61 | 0.53 | 0.67 |
Only index persons | 0.66 | 0.55 | 0.74 |
Median age at first event (years) | |||
Whole population | 15.58 | 17.76 | 13.76 |
Only index persons | 15.95 | 17.81 | 14.51 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 1329 | 660 | 669 |
Unadjusted period prevalence (%) | 0.30 | 0.26 | 0.34 |
Median age at first event (years) | 23.41 | 24.65 | 22.19 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint KRA_PSY_MENTALRET_EXMORE and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
KRA_PSY_MENTALRET_EXMORE | 4.664 [4.03, 5.39] | < 0.001 |
Birth year | 0.995 [0.99, 1.0] | 0.254 |
During the follow-up period (1.1.1998 — 31.12.2019), 1080 out of 9154 females with KRA_PSY_MENTALRET_EXMORE died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
KRA_PSY_MENTALRET_EXMORE | 3.916 [3.41, 4.49] | < 0.001 |
Birth year | 0.985 [0.98, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 1270 out of 12728 males with KRA_PSY_MENTALRET_EXMORE died.
Mortality risk
Mortality risk for people of age
years, who have KRA_PSY_MENTALRET_EXMORE.N-year risk | Females | Males |
---|---|---|
1 | 0.398% | 0.654% |
5 | 2.615% | 4.192% |
10 | 7.048% | 10.306% |
15 | 12.211% | 18.579% |
20 | 21.058% | 30.023% |
Relationships between endpoints
↥Index endpoint: KRA_PSY_MENTALRET_EXMORE – Mental retardation
GWS hits: 2