No definition available.
Respiratory conditions due to other external agents
EFO MESH Endpoint Browser PheWeb
J10_RESPCONDEXT
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
631 |
4. Check minimum number of eventsNone |
631 |
5. Include endpointsNone |
631 |
6. Filter based on genotype QC (FinnGen only) |
609 |
Control definitions (FinnGen only)
Control exclude
J10_EXTERLUNG
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
J60-J70
Name in latin
Morbositates respiratoriae ex aliis agentibus externis
Similar endpoints
↥List of similar endpoints to
Respiratory conditions due to other external agents
based on the number of shared cases.
Similar with more cases:
- Lung diseases due to external agents
- Diagnoses used for exclusion with ILD
- Diseases of the respiratory system
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5135 | 2989 | 2077 |
| Only index persons | 3638 | 2249 | 1389 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.07 | 0.09 | 0.06 |
| Only index persons | 0.07 | 0.08 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 69.92 | 70.17 | 69.46 |
| Only index persons | 67.98 | 67.98 | 67.97 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 609 | 353 | 256 |
| Unadjusted period prevalence (%) | 0.13 | 0.14 | 0.13 |
| Median age at first event (years) | 66.41 | 63.20 | 70.83 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint J10_RESPCONDEXT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_RESPCONDEXT | 2.553 [2.22, 2.94] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.283 |
During the follow-up period (1.1.1998 — 31.12.2019), 1081 out of 2197 females with J10_RESPCONDEXT died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_RESPCONDEXT | 4.277 [3.44, 5.32] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 953 out of 1460 males with J10_RESPCONDEXT died.
Mortality risk
Mortality risk for people of age
years, who have J10_RESPCONDEXT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.267% | 0.724% |
| 5 | 1.56% | 4.682% |
| 10 | 3.869% | 11.389% |
| 15 | 6.993% | 21.879% |
| 20 | 12.541% | 33.517% |
Relationships between endpoints
↥Index endpoint: J10_RESPCONDEXT – Respiratory conditions due to other external agents
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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