No definition available.
Drug-induced interstitial lung disorders, unspecified
DRUGADVERS_INTERSTITIAL_LUNG_DISORD_UNSPE
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
54 |
4. Check minimum number of eventsNone |
54 |
5. Include endpointsNone |
54 |
6. Filter based on genotype QC (FinnGen only) |
52 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF5
Similar endpoints
↥List of similar endpoints to
Drug-induced interstitial lung disorders, unspecified
based on the number of shared cases.
Similar with more cases:
- Respiratory conditions due to other external agents
- Lung diseases due to external agents
- Diagnoses used for exclusion with ILD
- Other pulmonary diagnosis
- Excluding asthma or asthma-COPD overlap
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 294 | 177 | 116 |
| Only index persons | 245 | 147 | 98 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.00 | 0.01 | 0.00 |
| Only index persons | 0.00 | 0.01 | 0.00 |
| Median age at first event (years) | |||
| Whole population | 70.11 | 70.84 | 68.94 |
| Only index persons | 68.88 | 69.62 | 67.77 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 52 | 35 | 17 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | 63.51 | 67.21 | 55.90 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint DRUGADVERS_INTERSTITIAL_LUNG_DISORD_UNSPE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| DRUGADVERS_INTERSTITIAL_LUNG_DISORD_UNSPE | 2.1 [1.45, 3.04] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.217 |
During the follow-up period (1.1.1998 — 31.12.2019), 62 out of 143 females with DRUGADVERS_INTERSTITIAL_LUNG_DISORD_UNSPE died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have DRUGADVERS_INTERSTITIAL_LUNG_DISORD_UNSPE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.214% | No data |
| 5 | 1.23% | No data |
| 10 | 3.312% | No data |
| 15 | 5.661% | No data |
| 20 | 9.969% | No data |
Relationships between endpoints
↥Index endpoint: DRUGADVERS_INTERSTITIAL_LUNG_DISORD_UNSPE – Drug-induced interstitial lung disorders, unspecified
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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