≡ Risteys
FG R11 + FR

Documentation Changelog GitHub Contact & Feedback

All influenza (not pneumonia)

DOID EFO Endpoint Browser PheWeb

INFLUENZA

influenza: An acute viral infection of the respiratory tract, occurring in isolated cases, in epidemics, or in pandemics; it is caused by serologically different strains of viruses (influenzaviruses) designated A, B, and C, has a 3-day incubation period, and usually lasts for 3 to 10 days. It is marked by inflammation of the nasal mucosa, pharynx, and conjunctiva; headache; myalgia; often fever, chills, and prostration; and occasionally involvement of the myocardium or central nervous system.

Suggest a new description

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — J10, J11
  • Hospital discharge: ICD-9 — 487
  • Hospital discharge: ICD-8 — 47[0-4]
  • Hospital discharge: excluded ICD-10 — J10.0, J11.0
  • Hospital discharge: excluded ICD-9 — 4870
  • Hospital discharge: excluded ICD-8 — 471
  • Cause of death: ICD-10 — J10, J11
  • Cause of death: ICD-9 — 487
  • Cause of death: ICD-8 — 47[0-4]
  • Cause of death: excluded ICD-10 — 4870
  • Cause of death: excluded ICD-9 — 471

2 out of 7 registries used, show all original rules.

6352

4. Check minimum number of events

None

6352

5. Include endpoints

None

6352

6. Filter based on genotype QC (FinnGen only)

6092

Control definitions (FinnGen only)

Control exclude J10_INFLUPNEU

Extra metadata

First used in FinnGen datafreeze DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 86242 35278 50464
Only index persons 71348 28413 42935
Unadjusted period prevalence (%)
Whole population 1.24 1.01 1.41
Only index persons 1.40 1.04 1.64
Median age at first event (years)
Whole population 31.37 46.65 20.44
Only index persons 29.72 43.82 20.39

-FinnGen-

Key figures

All Female Male
Number of individuals 6092 2591 3501
Unadjusted period prevalence (%) 1.44 1.02 1.76
Median age at first event (years) 35.51 48.53 25.87

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

↥

Association

Association between endpoint INFLUENZA and mortality.

Females

Parameter HR [95% CI] p-value
INFLUENZA 1.582 [1.4, 1.79] < 0.001
Birth year 0.995 [0.99, 1.0] 0.17

During the follow-up period (1.1.1998 — 31.12.2019), 4041 out of 21701 females with INFLUENZA died.

Males

Parameter HR [95% CI] p-value
INFLUENZA 1.74 [1.5, 2.02] < 0.001
Birth year 0.988 [0.98, 1.0] 0.008

During the follow-up period (1.1.1998 — 31.12.2019), 3925 out of 27684 males with INFLUENZA died.

Mortality risk

Mortality risk for people of age

years, who have INFLUENZA.

N-year risk Females Males
1 0.143% 0.345%
5 0.922% 1.856%
10 2.286% 4.968%
15 4.141% 9.375%
20 7.459% 16.064%

Relationships between endpoints

↥

Index endpoint: INFLUENZA – All influenza (not pneumonia)

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data