eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]
Postprocedural disorders of ear and mastoid process, not elsewhere classified
DOID EFO Endpoint Browser PheWeb
H8_POSTOP
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
260 |
6. Filter based on genotype QC (FinnGen only) |
244 |
Control definitions (FinnGen only)
Control exclude
H8_OTHEREAR
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Postprocedural disorders of ear and mastoid process, not elsewhere classified
based on the number of shared cases.
Similar with more cases:
- Other disorders of ear
- Diseases of the ear and mastoid process
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2836 | 1357 | 1468 |
| Only index persons | 2677 | 1286 | 1391 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | 0.04 |
| Only index persons | 0.05 | 0.05 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 61.03 | 64.13 | 58.11 |
| Only index persons | 60.48 | 63.48 | 57.72 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 244 | 115 | 129 |
| Unadjusted period prevalence (%) | 0.06 | 0.05 | 0.06 |
| Median age at first event (years) | 61.55 | 60.30 | 62.67 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint H8_POSTOP and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_POSTOP | 1.144 [0.98, 1.33] | 0.082 |
| Birth year | 0.996 [0.99, 1.0] | 0.295 |
During the follow-up period (1.1.1998 — 31.12.2019), 277 out of 1246 females with H8_POSTOP died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_POSTOP | 1.039 [0.89, 1.21] | 0.623 |
| Birth year | 0.989 [0.98, 1.0] | 0.021 |
During the follow-up period (1.1.1998 — 31.12.2019), 310 out of 1325 males with H8_POSTOP died.
Mortality risk
Mortality risk for people of age
years, who have H8_POSTOP.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.115% | 0.218% |
| 5 | 0.677% | 1.277% |
| 10 | 1.588% | 3.284% |
| 15 | 3.028% | 6.119% |
| 20 | 5.623% | 10.166% |
Relationships between endpoints
↥Index endpoint: H8_POSTOP – Postprocedural disorders of ear and mastoid process, not elsewhere classified
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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