eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]
Other/unspecified postprocedural disorders of ear and mastoid process
DOID EFO Endpoint Browser PheWeb
H8_POSTOPNAS
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
85 |
4. Check minimum number of eventsNone |
85 |
5. Include endpointsNone |
85 |
6. Filter based on genotype QC (FinnGen only) |
79 |
Control definitions (FinnGen only)
Control exclude
H8_OTHEREAR
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Other/unspecified postprocedural disorders of ear and mastoid process
based on the number of shared cases.
Similar with more cases:
- Postprocedural disorders of ear and mastoid process, not elsewhere classified
- Other disorders of ear
- Diseases of the ear and mastoid process
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 977 | 479 | 495 |
| Only index persons | 935 | 464 | 471 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 64.74 | 67.98 | 61.54 |
| Only index persons | 64.84 | 67.85 | 61.88 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 79 | 35 | 44 |
| Unadjusted period prevalence (%) | 0.02 | 0.01 | 0.02 |
| Median age at first event (years) | 65.08 | 60.26 | 68.92 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint H8_POSTOPNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_POSTOPNAS | 1.092 [0.84, 1.41] | 0.506 |
| Birth year | 0.991 [0.98, 1.0] | 0.038 |
During the follow-up period (1.1.1998 — 31.12.2019), 86 out of 440 females with H8_POSTOPNAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_POSTOPNAS | 1.324 [0.98, 1.79] | 0.067 |
| Birth year | 0.984 [0.97, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 96 out of 441 males with H8_POSTOPNAS died.
Mortality risk
Mortality risk for people of age
years, who have H8_POSTOPNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.087% | 0.227% |
| 5 | 0.539% | 1.316% |
| 10 | 1.37% | 3.49% |
| 15 | 2.665% | 6.444% |
| 20 | 4.665% | 10.797% |
Relationships between endpoints
↥Index endpoint: H8_POSTOPNAS – Other/unspecified postprocedural disorders of ear and mastoid process
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data