No definition available.
Recurrent cholesteatoma of postmastoidectomy cavity
H8_POSTMASTCHOLEASTOMA
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
104 |
4. Check minimum number of eventsNone |
104 |
5. Include endpointsNone |
104 |
6. Filter based on genotype QC (FinnGen only) |
100 |
Control definitions (FinnGen only)
Control exclude
H8_OTHEREAR
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H95
Name in latin
Cholesteatoma postoperativum recidivum auris mediae
Similar endpoints
↥List of similar endpoints to
Recurrent cholesteatoma of postmastoidectomy cavity
based on the number of shared cases.
Similar with more cases:
- Postprocedural disorders of ear and mastoid process, not elsewhere classified
- Other disorders of ear
- Diseases of the ear and mastoid process
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1043 | 467 | 574 |
| Only index persons | 986 | 440 | 546 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.02 |
| Only index persons | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 55.47 | 58.07 | 53.39 |
| Only index persons | 54.74 | 57.43 | 52.57 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 100 | 42 | 58 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.03 |
| Median age at first event (years) | 57.60 | 56.98 | 58.05 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint H8_POSTMASTCHOLEASTOMA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_POSTMASTCHOLEASTOMA | 0.987 [0.78, 1.24] | 0.91 |
| Birth year | 0.991 [0.98, 1.0] | 0.042 |
During the follow-up period (1.1.1998 — 31.12.2019), 78 out of 423 females with H8_POSTMASTCHOLEASTOMA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_POSTMASTCHOLEASTOMA | 1.045 [0.85, 1.29] | 0.679 |
| Birth year | 0.985 [0.98, 0.99] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 109 out of 516 males with H8_POSTMASTCHOLEASTOMA died.
Mortality risk
Mortality risk for people of age
years, who have H8_POSTMASTCHOLEASTOMA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.117% | 0.199% |
| 5 | 0.516% | 1.236% |
| 10 | 1.229% | 2.987% |
| 15 | 2.24% | 5.244% |
| 20 | 3.872% | 9.083% |
Relationships between endpoints
↥Index endpoint: H8_POSTMASTCHOLEASTOMA – Recurrent cholesteatoma of postmastoidectomy cavity
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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