No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
5050 |
6. Filter based on genotype QC (FinnGen only) |
4832 |
Control definitions (FinnGen only)
Control exclude
H7_CONJUNCTIVA
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Other disorders of conjunctiva
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 41385 | 21080 | 19871 |
| Only index persons | 37069 | 19603 | 17466 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.58 | 0.60 | 0.56 |
| Only index persons | 0.70 | 0.72 | 0.67 |
| Median age at first event (years) | |||
| Whole population | 59.62 | 59.82 | 59.72 |
| Only index persons | 59.28 | 59.41 | 59.14 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 4832 | 2631 | 2201 |
| Unadjusted period prevalence (%) | 1.07 | 1.03 | 1.11 |
| Median age at first event (years) | 60.69 | 58.23 | 63.63 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint H7_OTHERCONJ and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_OTHERCONJ | 1.106 [1.01, 1.21] | 0.029 |
| Birth year | 0.992 [0.98, 1.0] | 0.142 |
During the follow-up period (1.1.1998 — 31.12.2019), 2787 out of 17143 females with H7_OTHERCONJ died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_OTHERCONJ | 1.063 [0.97, 1.17] | 0.206 |
| Birth year | 0.991 [0.98, 1.0] | 0.04 |
During the follow-up period (1.1.1998 — 31.12.2019), 3093 out of 14980 males with H7_OTHERCONJ died.
Mortality risk
Mortality risk for people of age
years, who have H7_OTHERCONJ.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.07% | 0.2% |
| 5 | 0.512% | 1.248% |
| 10 | 1.305% | 3.367% |
| 15 | 2.645% | 6.612% |
| 20 | 4.581% | 11.182% |
Relationships between endpoints
↥Index endpoint: H7_OTHERCONJ – Other disorders of conjunctiva
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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