No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
738 |
4. Check minimum number of eventsNone |
738 |
5. Include endpointsNone |
738 |
6. Filter based on genotype QC (FinnGen only) |
715 |
Control definitions (FinnGen only)
Control exclude
H7_CONJUNCTIVA
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H11
Name in latin
Aliae morbositates vasculares et cystae conjunctivae
Similar endpoints
↥List of similar endpoints to
Other conjunctival vascular disorders and cysts
based on the number of shared cases.
Similar with more cases:
- Other disorders of conjunctiva
- Disorders of conjunctiva
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5855 | 3365 | 2462 |
| Only index persons | 5436 | 3191 | 2245 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.10 | 0.07 |
| Only index persons | 0.10 | 0.12 | 0.09 |
| Median age at first event (years) | |||
| Whole population | 55.86 | 55.85 | 55.92 |
| Only index persons | 55.47 | 55.40 | 55.57 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 715 | 455 | 260 |
| Unadjusted period prevalence (%) | 0.16 | 0.18 | 0.13 |
| Median age at first event (years) | 56.09 | 54.55 | 58.77 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint H7_CONJUVASC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CONJUVASC | 0.92 [0.81, 1.05] | 0.219 |
| Birth year | 0.994 [0.99, 1.0] | 0.16 |
During the follow-up period (1.1.1998 — 31.12.2019), 359 out of 2876 females with H7_CONJUVASC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CONJUVASC | 0.928 [0.81, 1.06] | 0.266 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 388 out of 2074 males with H7_CONJUVASC died.
Mortality risk
Mortality risk for people of age
years, who have H7_CONJUVASC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.071% | 0.187% |
| 5 | 0.519% | 1.012% |
| 10 | 1.248% | 2.506% |
| 15 | 2.497% | 4.787% |
| 20 | 4.41% | 8.114% |
Relationships between endpoints
↥Index endpoint: H7_CONJUVASC – Other conjunctival vascular disorders and cysts
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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