alcohol withdrawal delirium: An acute organic mental disorder induced by cessation or reduction in chronic alcohol consumption. Clinical characteristics include confusion; delusions; vivid hallucinations; tremor; agitation; insomnia; and signs of autonomic hyperactivity (e.g., elevated blood pressure and heart rate, dilated pupils, and diaphoresis). This condition may occasionally be fatal. It was formerly called delirium tremens. (From Adams et al., Principles of Neurology, 6th ed, p1175)
Mental and behavioural disorders due to use of volatile solvents
DOID EFO Endpoint Browser PheWeb
F5_SOLVENT
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
97 |
4. Check minimum number of eventsNone |
97 |
5. Include endpointsNone |
97 |
6. Filter based on genotype QC (FinnGen only) |
89 |
Control definitions (FinnGen only)
Control exclude
F5_SUBSNOALCO
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
F10-F19
Name in latin
Perturbationes mentis et modi se gerendi ex usu solventium volatilium
Similar endpoints
↥List of similar endpoints to
Mental and behavioural disorders due to use of volatile solvents
based on the number of shared cases.
Similar with more cases:
- Substance use, excluding alcohol
- Substance abuse
- Substance abuse
- Mental and behavioural disorders due to psychoactive substance use
- Any mental disorder
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1225 | 317 | 902 |
| Only index persons | 1060 | 291 | 769 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.01 | 0.03 |
| Only index persons | 0.02 | 0.01 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 28.99 | 26.78 | 29.71 |
| Only index persons | 28.18 | 26.16 | 28.94 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 89 | 33 | 56 |
| Unadjusted period prevalence (%) | 0.02 | 0.01 | 0.03 |
| Median age at first event (years) | 27.11 | 25.49 | 28.07 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint F5_SOLVENT and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_SOLVENT | 5.861 [3.8, 9.04] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 151 out of 599 males with F5_SOLVENT died.
Mortality risk
Mortality risk for people of age
years, who have F5_SOLVENT.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 1.15% |
| 5 | No data | 6.035% |
| 10 | No data | 15.889% |
| 15 | No data | 27.945% |
| 20 | No data | 43.88% |
Relationships between endpoints
↥Index endpoint: F5_SOLVENT – Mental and behavioural disorders due to use of volatile solvents
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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