Benign neoplasm of male genital organs

CD2_BENIGN_MALE_GEN

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

only males

207946

2. Check conditions

None

207946

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D29
  • Cause of death: ICD-10 D29

2 out of 7 registries used, show all original rules.

556

4. Check minimum number of events

None

556

5. Include endpoints

673

6. Filter based on genotype QC (FinnGen only)

651

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF3
Parent code in ICD-10 D10-D36
Name in latin Neoplasmata benigna organorum genitalium masculinorum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5564 - 5564
Only index persons 4801 - 4801
Unadjusted period prevalence (%)
Whole population 0.16 - 0.16
Only index persons 0.18 - 0.18
Median age at first event (years)
Whole population - - 52.91
Only index persons - - 50.02

-FinnGen-

Key figures

All Female Male
Number of individuals 651 - 651
Unadjusted period prevalence (%) 0.33 - 0.33
Median age at first event (years) 58.18 - 58.18

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_MALE_GEN and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_MALE_GEN 1.301 [1.15, 1.47] < 0.001
Birth year 0.986 [0.98, 1.0] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 965 out of 3809 males with CD2_BENIGN_MALE_GEN died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_MALE_GEN.

N-year risk Females Males
1 No data 0.238%
5 No data 1.447%
10 No data 3.479%
15 No data 6.681%
20 No data 11.102%

Relationships between endpoints

Index endpoint: CD2_BENIGN_MALE_GEN – Benign neoplasm of male genital organs

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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