testicular carcinoma: A primary or metastatic malignant neoplasm that affects the testis. Representative examples include seminoma, embryonal carcinoma, sarcoma, leukemia, and lymphoma.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleonly males |
207946 |
2. Check conditionsNone |
207946 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
139 |
4. Check minimum number of eventsNone |
139 |
5. Include endpointsNone |
139 |
6. Filter based on genotype QC (FinnGen only) |
133 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D29
Name in latin
Neoplasma benignum testis
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Testis
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Testis
- Benign neoplasm of male genital organs
- Benign neoplasm of male genital organs
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1309 | - | 1309 |
| Only index persons | 1140 | - | 1140 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | - | 0.04 |
| Only index persons | 0.04 | - | 0.04 |
| Median age at first event (years) | |||
| Whole population | - | - | 39.28 |
| Only index persons | - | - | 36.49 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 133 | - | 133 |
| Unadjusted period prevalence (%) | 0.07 | - | 0.07 |
| Median age at first event (years) | 47.64 | - | 47.64 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_TESTIS and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_TESTIS | 1.218 [0.97, 1.53] | 0.089 |
| Birth year | 0.987 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 128 out of 807 males with CD2_BENIGN_TESTIS died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_TESTIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.273% |
| 5 | No data | 1.509% |
| 10 | No data | 3.655% |
| 15 | No data | 6.935% |
| 20 | No data | 11.538% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_TESTIS – Benign neoplasm: Testis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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