Benign neoplasm: Epididymis

CD2_BENIGN_EPIDIDYMIS

testicular carcinoma: A primary or metastatic malignant neoplasm that affects the testis. Representative examples include seminoma, embryonal carcinoma, sarcoma, leukemia, and lymphoma.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

only males

207946

2. Check conditions

None

207946

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D29.3&
  • Hospital discharge: ICD-9 2223
  • Cause of death: ICD-10 D29.3&
  • Cause of death: ICD-9 2223

2 out of 7 registries used, show all original rules.

102

4. Check minimum number of events

None

102

5. Include endpoints

None

102

6. Filter based on genotype QC (FinnGen only)

98

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D29
Name in latin Neoplasma benignum epididymidis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 908 - 908
Only index persons 837 - 837
Unadjusted period prevalence (%)
Whole population 0.03 - 0.03
Only index persons 0.03 - 0.03
Median age at first event (years)
Whole population - - 51.60
Only index persons - - 50.67

-FinnGen-

Key figures

All Female Male
Number of individuals 98 - 98
Unadjusted period prevalence (%) 0.05 - 0.05
Median age at first event (years) 54.12 - 54.12

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_EPIDIDYMIS and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_EPIDIDYMIS 0.951 [0.75, 1.2] 0.673
Birth year 0.985 [0.98, 0.99] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 98 out of 637 males with CD2_BENIGN_EPIDIDYMIS died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_EPIDIDYMIS.

N-year risk Females Males
1 No data 0.15%
5 No data 1.044%
10 No data 2.681%
15 No data 5.038%
20 No data 8.452%

Relationships between endpoints

Index endpoint: CD2_BENIGN_EPIDIDYMIS – Benign neoplasm: Epididymis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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