Benign neoplasm: Penis

CD2_BENIGN_PENIS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

only males

207946

2. Check conditions

None

207946

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D29.0&
  • Hospital discharge: ICD-9 2221
  • Hospital discharge: ICD-8 2221
  • Cause of death: ICD-10 D29.0&
  • Cause of death: ICD-9 2221
  • Cause of death: ICD-8 2221

2 out of 7 registries used, show all original rules.

65

4. Check minimum number of events

None

65

5. Include endpoints

None

65

6. Filter based on genotype QC (FinnGen only)

65

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D29
Name in latin Neoplasma benignum penis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 661 - 661
Only index persons 598 - 598
Unadjusted period prevalence (%)
Whole population 0.02 - 0.02
Only index persons 0.02 - 0.02
Median age at first event (years)
Whole population - - 37.45
Only index persons - - 35.65

-FinnGen-

Key figures

All Female Male
Number of individuals 65 - 65
Unadjusted period prevalence (%) 0.03 - 0.03
Median age at first event (years) 43.25 - 43.25

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_PENIS and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_PENIS 1.07 [0.79, 1.44] 0.656
Birth year 0.988 [0.98, 1.0] 0.013

During the follow-up period (1.1.1998 — 31.12.2019), 74 out of 444 males with CD2_BENIGN_PENIS died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_PENIS.

N-year risk Females Males
1 No data 0.182%
5 No data 1.191%
10 No data 3.334%
15 No data 6.002%
20 No data 10.271%

Relationships between endpoints

Index endpoint: CD2_BENIGN_PENIS – Benign neoplasm: Penis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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