retroperitoneal cancer: An organ system cancer located_in the retroperitoneal space that is manifested in retroperitoneal space in the abdominal cavity behind the peritoneum.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
3194 |
4. Check minimum number of eventsNone |
3194 |
5. Include endpoints |
3391 |
6. Filter based on genotype QC (FinnGen only) |
3276 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10-D36
Similar endpoints
↥List of similar endpoints to
Benign neoplasm of eye and adnexa
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm of eye and adnexa
- Benign neoplasms
- Benign neoplasms
- Neoplasms
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 25204 | 14659 | 10446 |
| Only index persons | 23577 | 13924 | 9653 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.37 | 0.42 | 0.29 |
| Only index persons | 0.45 | 0.51 | 0.37 |
| Median age at first event (years) | |||
| Whole population | 59.42 | 59.87 | 58.81 |
| Only index persons | 59.42 | 59.84 | 58.81 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3276 | 1974 | 1302 |
| Unadjusted period prevalence (%) | 0.73 | 0.78 | 0.65 |
| Median age at first event (years) | 61.22 | 59.00 | 64.59 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_EYE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_EYE | 0.92 [0.83, 1.02] | 0.13 |
| Birth year | 0.996 [0.99, 1.0] | 0.338 |
During the follow-up period (1.1.1998 — 31.12.2019), 1518 out of 11421 females with CD2_BENIGN_EYE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_EYE | 0.948 [0.84, 1.07] | 0.39 |
| Birth year | 0.987 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 1366 out of 7991 males with CD2_BENIGN_EYE died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_EYE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.078% | 0.152% |
| 5 | 0.547% | 1.045% |
| 10 | 1.361% | 2.799% |
| 15 | 2.655% | 5.351% |
| 20 | 4.7% | 8.991% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_EYE – Benign neoplasm of eye and adnexa
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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