retinal cancer: A malignant neoplasm involving the retina.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
165 |
4. Check minimum number of eventsNone |
165 |
5. Include endpointsNone |
165 |
6. Filter based on genotype QC (FinnGen only) |
160 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D31
Name in latin
Neoplasma benignum retinae
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Retina
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Retina
- Benign neoplasm of eye and adnexa
- Benign neoplasm of eye and adnexa
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1303 | 829 | 465 |
| Only index persons | 1197 | 785 | 412 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.01 |
| Only index persons | 0.02 | 0.03 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 60.48 | 61.23 | 59.15 |
| Only index persons | 60.20 | 61.07 | 58.54 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 160 | 89 | 71 |
| Unadjusted period prevalence (%) | 0.04 | 0.03 | 0.04 |
| Median age at first event (years) | 57.92 | 52.21 | 65.07 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_RETINA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_RETINA | 1.033 [0.85, 1.25] | 0.737 |
| Birth year | 0.994 [0.98, 1.0] | 0.155 |
During the follow-up period (1.1.1998 — 31.12.2019), 140 out of 738 females with CD2_BENIGN_RETINA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_RETINA | 0.984 [0.75, 1.29] | 0.909 |
| Birth year | 0.989 [0.98, 1.0] | 0.021 |
During the follow-up period (1.1.1998 — 31.12.2019), 92 out of 406 males with CD2_BENIGN_RETINA died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_RETINA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.112% | 0.176% |
| 5 | 0.644% | 1.224% |
| 10 | 1.531% | 2.973% |
| 15 | 2.774% | 5.538% |
| 20 | 4.867% | 9.406% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_RETINA – Benign neoplasm: Retina
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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