brain neoplasm: A neoplasm (disease) that involves the brain.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
187 |
4. Check minimum number of eventsNone |
187 |
5. Include endpointsNone |
187 |
6. Filter based on genotype QC (FinnGen only) |
181 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D31
Name in latin
Neoplasma benignum orbitae non specificatum
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Orbit, unspecified
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Orbit, unspecified
- Benign neoplasm of eye and adnexa
- Benign neoplasm of eye and adnexa
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1703 | 988 | 701 |
| Only index persons | 1480 | 873 | 607 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.03 | 0.02 |
| Only index persons | 0.03 | 0.03 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 50.29 | 50.56 | 49.71 |
| Only index persons | 49.65 | 50.35 | 48.65 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 181 | 116 | 65 |
| Unadjusted period prevalence (%) | 0.04 | 0.05 | 0.03 |
| Median age at first event (years) | 54.39 | 52.16 | 58.38 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_ORBIT_NOS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_ORBIT_NOS | 1.274 [1.0, 1.63] | 0.051 |
| Birth year | 0.99 [0.98, 1.0] | 0.051 |
During the follow-up period (1.1.1998 — 31.12.2019), 108 out of 648 females with CD2_BENIGN_ORBIT_NOS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_ORBIT_NOS | 1.337 [1.0, 1.79] | 0.053 |
| Birth year | 0.984 [0.97, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 90 out of 444 males with CD2_BENIGN_ORBIT_NOS died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_ORBIT_NOS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.107% | 0.224% |
| 5 | 0.624% | 1.468% |
| 10 | 1.459% | 3.587% |
| 15 | 2.954% | 6.69% |
| 20 | 5.353% | 11.526% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_ORBIT_NOS – Benign neoplasm: Orbit, unspecified
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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