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Lack of expected normal physiological development

R18_LACK_EXPEC_NORMAL_PHYSIO_DEVELOPMENT

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 R62
  • Cause of death: ICD-10 R62

2 out of 7 registries used, show all original rules.

990

4. Check minimum number of events

None

990

5. Include endpoints

990

6. Filter based on genotype QC (FinnGen only)

915

Control definitions (FinnGen only)

Control exclude R18_GENERAL_SYMPTOMS_SIGNS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF9
Parent code in ICD-10 R[5-6]
Name in latin Absentia progressus physiologici normalis exspectati

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 915 471 444
Unadjusted period prevalence (%) 0.20 0.18 0.22
Median age at first event (years) 3.65 4.14 3.12

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: R18_LACK_EXPEC_NORMAL_PHYSIO_DEVELOPMENT – Lack of expected normal physiological development

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).