This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Other disturbances of cerebral status of newborn
P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
43 |
4. Check minimum number of eventsNone |
43 |
5. Include endpointsNone |
43 |
6. Filter based on genotype QC (FinnGen only) |
40 |
Control definitions (FinnGen only)
Control exclude
P16_OTH_DISORD_ORIGINA_PERINA_PERIOD
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P9
Name in latin
Aliae perturbationes status cerebralis neonati
Similar endpoints
↥List of similar endpoints to
Other disturbances of cerebral status of newborn
based on the number of shared cases.
Similar with more cases:
- Other disorders originating in the perinatal period
- Certain conditions originating in the perinatal period
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1980 | 844 | 1132 |
| Only index persons | 857 | 361 | 496 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.02 | 0.03 |
| Only index persons | 0.02 | 0.01 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 0.15 | 0.00 | 0.00 |
| Only index persons | 0.01 | 0.01 | 0.01 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 40 | 14 | 26 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | 0.00 | 0.01 | 0.00 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
Mortality – FinRegistry
↥Association
Association between endpoint P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO | 8.612 [3.55, 20.9] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.042 |
During the follow-up period (1.1.1998 — 31.12.2019), 54 out of 695 females with P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO | 11.971 [4.15, 34.5] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.022 |
During the follow-up period (1.1.1998 — 31.12.2019), 64 out of 949 males with P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO died.
Mortality risk
Mortality risk for people of age
years, who have P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.702% | 2.331% |
| 5 | 4.077% | 12.945% |
| 10 | 9.595% | 29.693% |
| 15 | 18.288% | 51.317% |
| 20 | 29.999% | 72.107% |
Relationships between endpoints
↥Index endpoint: P16_OTH_DISTU_CEREBRAL_STATUS_NEWBO – Other disturbances of cerebral status of newborn
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data