No definition available.
Other disorders originating in the perinatal period
P16_OTH_DISORD_ORIGINA_PERINA_PERIOD
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
338 |
4. Check minimum number of eventsNone |
338 |
5. Include endpoints |
338 |
6. Filter based on genotype QC (FinnGen only) |
318 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P
Name in latin
Aliae morbositates origine perinatales
Other disorders originating in the perinatal period
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 19070 | 9095 | 9959 |
| Only index persons | 8108 | 4005 | 4103 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.27 | 0.26 | 0.28 |
| Only index persons | 0.15 | 0.15 | 0.16 |
| Median age at first event (years) | |||
| Whole population | 0.08 | 0.03 | 0.03 |
| Only index persons | 0.04 | 0.06 | 0.03 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 318 | 205 | 113 |
| Unadjusted period prevalence (%) | 0.07 | 0.08 | 0.06 |
| Median age at first event (years) | 0.57 | 0.85 | 0.06 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint P16_OTH_DISORD_ORIGINA_PERINA_PERIOD and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| P16_OTH_DISORD_ORIGINA_PERINA_PERIOD | 3.808 [2.79, 5.19] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.641 |
During the follow-up period (1.1.1998 — 31.12.2019), 143 out of 8343 females with P16_OTH_DISORD_ORIGINA_PERINA_PERIOD died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| P16_OTH_DISORD_ORIGINA_PERINA_PERIOD | 3.23 [2.24, 4.66] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 145 out of 9291 males with P16_OTH_DISORD_ORIGINA_PERINA_PERIOD died.
Mortality risk
Mortality risk for people of age
years, who have P16_OTH_DISORD_ORIGINA_PERINA_PERIOD.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.346% | 0.536% |
| 5 | 2.175% | 3.4% |
| 10 | 5.482% | 9.188% |
| 15 | 10.433% | 16.711% |
| 20 | 18.473% | 26.947% |
Relationships between endpoints
↥Index endpoint: P16_OTH_DISORD_ORIGINA_PERINA_PERIOD – Other disorders originating in the perinatal period
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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