No definition available.
Complications predominantly related to the puerperium
DOID EFO Endpoint Browser PheWeb
O15_COMPLIC_PUERP
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleonly females |
265735 |
2. Check conditionsNone |
265735 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
5955 |
4. Check minimum number of eventsNone |
5955 |
5. Include endpoints |
11013 |
6. Filter based on genotype QC (FinnGen only) |
10598 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF3
Complications predominantly related to the puerperium
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 85667 | 85667 | - |
| Only index persons | 83576 | 83576 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 2.45 | 2.45 | - |
| Only index persons | 3.07 | 3.07 | - |
| Median age at first event (years) | |||
| Whole population | - | 28.24 | - |
| Only index persons | - | 28.24 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 10598 | 10598 | - |
| Unadjusted period prevalence (%) | 4.16 | 4.16 | - |
| Median age at first event (years) | 28.65 | 28.65 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint O15_COMPLIC_PUERP and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| O15_COMPLIC_PUERP | 0.609 [0.51, 0.73] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.298 |
During the follow-up period (1.1.1998 — 31.12.2019), 215 out of 40081 females with O15_COMPLIC_PUERP died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have O15_COMPLIC_PUERP.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.058% | No data |
| 5 | 0.406% | No data |
| 10 | 0.948% | No data |
| 15 | 1.831% | No data |
| 20 | 3.258% | No data |
Relationships between endpoints
↥Index endpoint: O15_COMPLIC_PUERP – Complications predominantly related to the puerperium
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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