Puerperal sepsis

O15_PUERP_SEPSIS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

only females

265735

2. Check conditions

None

265735

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O85
  • Hospital discharge: ICD-9 670
  • Hospital discharge: ICD-8 670
  • Cause of death: ICD-10 O85
  • Cause of death: ICD-9 670
  • Cause of death: ICD-8 670

2 out of 7 registries used, show all original rules.

4857

4. Check minimum number of events

None

4857

5. Include endpoints

None

4857

6. Filter based on genotype QC (FinnGen only)

4724

Control definitions (FinnGen only)

Control exclude O15_COMPLIC_PUERP

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF5
Parent code in ICD-10 O85-O92
Name in latin Sepsis puerperalis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 37880 37880 -
Only index persons 36538 36538 -
Unadjusted period prevalence (%)
Whole population 1.08 1.08 -
Only index persons 1.34 1.34 -
Median age at first event (years)
Whole population - 26.20 -
Only index persons - 26.19 -

-FinnGen-

Key figures

All Female Male
Number of individuals 4724 4724 -
Unadjusted period prevalence (%) 1.86 1.86 -
Median age at first event (years) 26.35 26.35 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Association

Association between endpoint O15_PUERP_SEPSIS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_PUERP_SEPSIS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: O15_PUERP_SEPSIS – Puerperal sepsis

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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