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Other disorders of breast and lactation associated with childbirth

EFO MESH Endpoint Browser PheWeb

O15_BREAST_LACT_OTHER_DIS

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

only females

265735

2. Check conditions

None

265735

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — O92
  • Hospital discharge: ICD-9 — 676
  • Hospital discharge: ICD-8 — 6780[089]
  • Cause of death: ICD-10 — O92
  • Cause of death: ICD-9 — 676
  • Cause of death: ICD-8 — 6780[089]

2 out of 7 registries used, show all original rules.

629

4. Check minimum number of events

None

629

5. Include endpoints

None

629

6. Filter based on genotype QC (FinnGen only)

602

Control definitions (FinnGen only)

Control exclude O15_COMPLIC_PUERP

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF5
Parent code in ICD-10 O85-O92
Name in latin Alii morbositates mammmae et perturbationes lactationis ad partum adjunctae

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3627 3627 -
Only index persons 3580 3580 -
Unadjusted period prevalence (%)
Whole population 0.10 0.10 -
Only index persons 0.13 0.13 -
Median age at first event (years)
Whole population - 31.25 -
Only index persons - 31.23 -

-FinnGen-

Key figures

All Female Male
Number of individuals 602 602 -
Unadjusted period prevalence (%) 0.24 0.24 -
Median age at first event (years) 31.57 31.57 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

Mortality – FinRegistry

↥

Association

Association between endpoint O15_BREAST_LACT_OTHER_DIS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_BREAST_LACT_OTHER_DIS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

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Index endpoint: O15_BREAST_LACT_OTHER_DIS – Other disorders of breast and lactation associated with childbirth

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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