Other puerperal infections

O15_PUERP_INFECT_OTHER

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

only females

265735

2. Check conditions

None

265735

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O86
  • Hospital discharge: ICD-8 67299
  • Cause of death: ICD-10 O86
  • Cause of death: ICD-8 67299

2 out of 7 registries used, show all original rules.

2979

4. Check minimum number of events

None

2979

5. Include endpoints

None

2979

6. Filter based on genotype QC (FinnGen only)

2833

Control definitions (FinnGen only)

Control exclude O15_COMPLIC_PUERP

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF5
Parent code in ICD-10 O85-O92
Name in latin Aliae infectiones puerperales

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 23424 23424 -
Only index persons 23174 23174 -
Unadjusted period prevalence (%)
Whole population 0.67 0.67 -
Only index persons 0.85 0.85 -
Median age at first event (years)
Whole population - 29.65 -
Only index persons - 29.65 -

-FinnGen-

Key figures

All Female Male
Number of individuals 2833 2833 -
Unadjusted period prevalence (%) 1.11 1.11 -
Median age at first event (years) 30.43 30.43 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Association

Association between endpoint O15_PUERP_INFECT_OTHER and mortality.

Females

Parameter HR [95% CI] p-value
O15_PUERP_INFECT_OTHER 0.713 [0.56, 0.9] 0.005
Birth year 0.997 [0.99, 1.01] 0.423

During the follow-up period (1.1.1998 — 31.12.2019), 97 out of 18881 females with O15_PUERP_INFECT_OTHER died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_PUERP_INFECT_OTHER.

N-year risk Females Males
1 0.052% No data
5 0.387% No data
10 1.098% No data
15 1.99% No data
20 3.635% No data

Relationships between endpoints

Index endpoint: O15_PUERP_INFECT_OTHER – Other puerperal infections

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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