No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
6870 |
4. Check minimum number of eventsNone |
6870 |
5. Include endpointsNone |
6870 |
6. Filter based on genotype QC (FinnGen only) |
6651 |
Control definitions (FinnGen only)
Control exclude
M13_DORSOPATHY
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M54
Name in latin
Radiculopathia
Similar endpoints
↥List of similar endpoints to
Radiculopathy
based on the number of shared cases.
Similar with more cases:
- Dorsalgia
- Dorsopathies
- Pain (limb, back, neck, head abdominally)
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 59475 | 30456 | 28366 |
| Only index persons | 48430 | 26549 | 21881 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.83 | 0.87 | 0.79 |
| Only index persons | 0.91 | 0.98 | 0.84 |
| Median age at first event (years) | |||
| Whole population | 48.91 | 49.18 | 48.55 |
| Only index persons | 47.58 | 48.07 | 46.98 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 6651 | 3603 | 3048 |
| Unadjusted period prevalence (%) | 1.47 | 1.42 | 1.53 |
| Median age at first event (years) | 48.24 | 47.06 | 49.63 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint M13_RADICULOPATHY and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_RADICULOPATHY | 1.183 [1.07, 1.31] | 0.002 |
| Birth year | 0.993 [0.98, 1.0] | 0.075 |
During the follow-up period (1.1.1998 — 31.12.2019), 1712 out of 13922 females with M13_RADICULOPATHY died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_RADICULOPATHY | 1.235 [1.11, 1.37] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 1820 out of 11266 males with M13_RADICULOPATHY died.
Mortality risk
Mortality risk for people of age
years, who have M13_RADICULOPATHY.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.118% | 0.209% |
| 5 | 0.689% | 1.412% |
| 10 | 1.786% | 3.69% |
| 15 | 3.203% | 6.902% |
| 20 | 5.717% | 11.824% |
Relationships between endpoints
↥Index endpoint: M13_RADICULOPATHY – Radiculopathy
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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