No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
356 |
4. Check minimum number of eventsNone |
356 |
5. Include endpointsNone |
356 |
6. Filter based on genotype QC (FinnGen only) |
354 |
Control definitions (FinnGen only)
Control exclude
M13_ARTHROPATHIES
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M12
Name in latin
Rheumatismus palindromicus
Similar endpoints
↥List of similar endpoints to
Palindromic rheumatism
based on the number of shared cases.
Similar with more cases:
- Other specific arthropathies
- Polyarthropathies
- Finngen Rheumatological endpoints
- Arthropathies
- Diseases of the musculoskeletal system and connective tissue
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1936 | 1191 | 735 |
| Only index persons | 1767 | 1120 | 647 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.03 | 0.02 |
| Only index persons | 0.04 | 0.04 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 52.21 | 51.50 | 53.40 |
| Only index persons | 51.77 | 51.02 | 53.08 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 354 | 222 | 132 |
| Unadjusted period prevalence (%) | 0.08 | 0.09 | 0.07 |
| Median age at first event (years) | 52.25 | 50.47 | 55.25 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint M13_PALINDROMIC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_PALINDROMIC | 1.065 [0.85, 1.33] | 0.575 |
| Birth year | 0.998 [0.99, 1.01] | 0.617 |
During the follow-up period (1.1.1998 — 31.12.2019), 93 out of 915 females with M13_PALINDROMIC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_PALINDROMIC | 1.457 [1.19, 1.78] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.009 |
During the follow-up period (1.1.1998 — 31.12.2019), 120 out of 583 males with M13_PALINDROMIC died.
Mortality risk
Mortality risk for people of age
years, who have M13_PALINDROMIC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.084% | 0.246% |
| 5 | 0.568% | 1.694% |
| 10 | 1.612% | 4.199% |
| 15 | 3.344% | 7.854% |
| 20 | 5.978% | 13.26% |
Relationships between endpoints
↥Index endpoint: M13_PALINDROMIC – Palindromic rheumatism
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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