No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
18019 |
4. Check minimum number of eventsNone |
18019 |
5. Include endpointsNone |
18019 |
6. Filter based on genotype QC (FinnGen only) |
17310 |
Control definitions (FinnGen only)
Control exclude
M13_DORSOPATHY
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Other/unspecified dorsalgia
based on the number of shared cases.
Similar with more cases:
- Dorsalgia
- Dorsopathies
- Pain (limb, back, neck, head abdominally)
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 166898 | 96628 | 68891 |
| Only index persons | 145945 | 85907 | 60038 |
| Unadjusted period prevalence (%) | |||
| Whole population | 2.41 | 2.77 | 1.92 |
| Only index persons | 2.80 | 3.16 | 2.29 |
| Median age at first event (years) | |||
| Whole population | 50.58 | 52.83 | 47.43 |
| Only index persons | 48.32 | 50.54 | 45.13 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 17310 | 10883 | 6427 |
| Unadjusted period prevalence (%) | 3.89 | 4.27 | 3.23 |
| Median age at first event (years) | 49.58 | 48.00 | 52.26 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint M13_DORSALGIANAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_DORSALGIANAS | 1.572 [1.44, 1.71] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.009 |
During the follow-up period (1.1.1998 — 31.12.2019), 16849 out of 72399 females with M13_DORSALGIANAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_DORSALGIANAS | 1.834 [1.66, 2.02] | < 0.001 |
| Birth year | 0.984 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 10607 out of 48859 males with M13_DORSALGIANAS died.
Mortality risk
Mortality risk for people of age
years, who have M13_DORSALGIANAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.134% | 0.335% |
| 5 | 0.723% | 1.842% |
| 10 | 1.756% | 4.535% |
| 15 | 3.473% | 8.702% |
| 20 | 6.084% | 14.901% |
Relationships between endpoints
↥Index endpoint: M13_DORSALGIANAS – Other/unspecified dorsalgia
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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