Tuberculosis, Cutaneous: Tuberculosis of the skin. It includes scrofuloderma and tuberculid, but not LUPUS VULGARIS.
Other local infections of skin and subcutaneous tissue
DOID EFO Endpoint Browser PheWeb
L12_INFECT_SKIN_OTHER
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
3700 |
6. Filter based on genotype QC (FinnGen only) |
3553 |
Control definitions (FinnGen only)
Control exclude
L12_INFECT_SKIN
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Other local infections of skin and subcutaneous tissue
based on the number of shared cases.
Similar with more cases:
- Infections of the skin and subcutaneous tissue
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No data for upset plot.
No data for upset table.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 34982 | 15741 | 18936 |
| Only index persons | 29006 | 13360 | 15646 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.49 | 0.45 | 0.53 |
| Only index persons | 0.55 | 0.49 | 0.60 |
| Median age at first event (years) | |||
| Whole population | 47.14 | 48.83 | 45.62 |
| Only index persons | 47.11 | 49.03 | 45.48 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3553 | 1797 | 1756 |
| Unadjusted period prevalence (%) | 0.79 | 0.71 | 0.88 |
| Median age at first event (years) | 53.73 | 51.36 | 56.16 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint L12_INFECT_SKIN_OTHER and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_INFECT_SKIN_OTHER | 2.319 [2.03, 2.65] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.336 |
During the follow-up period (1.1.1998 — 31.12.2019), 2422 out of 10980 females with L12_INFECT_SKIN_OTHER died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_INFECT_SKIN_OTHER | 2.305 [1.95, 2.73] | < 0.001 |
| Birth year | 0.983 [0.92, 1.05] | 0.608 |
During the follow-up period (1.1.1998 — 31.12.2019), 2964 out of 12686 males with L12_INFECT_SKIN_OTHER died.
Mortality risk
Mortality risk for people of age
years, who have L12_INFECT_SKIN_OTHER.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.164% | 0.433% |
| 5 | 1.23% | 2.133% |
| 10 | 3.24% | 5.789% |
| 15 | 6.253% | 10.672% |
| 20 | 11.096% | 17.629% |
Relationships between endpoints
↥Index endpoint: L12_INFECT_SKIN_OTHER – Other local infections of skin and subcutaneous tissue
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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