Erythrasma

L12_ERYTHRASMA

erythrasma: a skin disease that causes brown, scaly skin patches. It is caused by the Gram-positive bacterium Corynebacterium minutissimum. It is prevalent among diabetics and the obese, and in warm climates; it is worsened by wearing occlusive clothing.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L08.1
  • Hospital discharge: ICD-9 390
  • Cause of death: ICD-10 L08.1
  • Cause of death: ICD-9 390

2 out of 7 registries used, show all original rules.

72

4. Check minimum number of events

None

72

5. Include endpoints

None

72

6. Filter based on genotype QC (FinnGen only)

70

Control definitions (FinnGen only)

Control exclude L12_INFECT_SKIN

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF4
Parent code in ICD-10 L08
Name in latin Erythrasma

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 476 191 281
Only index persons 408 160 248
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 50.66 50.13 50.99
Only index persons 47.94 47.52 48.22

-FinnGen-

Key figures

All Female Male
Number of individuals 70 24 46
Unadjusted period prevalence (%) 0.02 0.01 0.02
Median age at first event (years) 53.47 55.35 52.49

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

Mortality – FinRegistry

Association

Association between endpoint L12_ERYTHRASMA and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_ERYTHRASMA.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: L12_ERYTHRASMA – Erythrasma

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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