No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
662 |
4. Check minimum number of eventsNone |
662 |
5. Include endpointsNone |
662 |
6. Filter based on genotype QC (FinnGen only) |
643 |
Control definitions (FinnGen only)
Control exclude
L12_INFECT_SKIN
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L08
Name in latin
Pyoderma
Similar endpoints
↥List of similar endpoints to
Pyoderma
based on the number of shared cases.
Similar with more cases:
- Other local infections of skin and subcutaneous tissue
- Infections of the skin and subcutaneous tissue
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7378 | 3141 | 4153 |
| Only index persons | 5683 | 2533 | 3150 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.10 | 0.09 | 0.12 |
| Only index persons | 0.11 | 0.09 | 0.12 |
| Median age at first event (years) | |||
| Whole population | 39.59 | 39.40 | 39.51 |
| Only index persons | 37.57 | 38.25 | 37.03 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 643 | 328 | 315 |
| Unadjusted period prevalence (%) | 0.14 | 0.13 | 0.16 |
| Median age at first event (years) | 43.30 | 41.73 | 44.94 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint L12_PYODERMA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_PYODERMA | 2.971 [2.44, 3.62] | < 0.001 |
| Birth year | 0.996 [0.99, 1.01] | 0.409 |
During the follow-up period (1.1.1998 — 31.12.2019), 506 out of 2065 females with L12_PYODERMA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_PYODERMA | 3.025 [2.54, 3.61] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.028 |
During the follow-up period (1.1.1998 — 31.12.2019), 688 out of 2431 males with L12_PYODERMA died.
Mortality risk
Mortality risk for people of age
years, who have L12_PYODERMA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.308% | 0.658% |
| 5 | 1.762% | 3.384% |
| 10 | 4.729% | 8.653% |
| 15 | 8.484% | 16.462% |
| 20 | 14.789% | 26.195% |
Relationships between endpoints
↥Index endpoint: L12_PYODERMA – Pyoderma
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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