folliculitis: the infection and inflammation of one or more hair follicles. The condition may occur anywhere on the skin with the exception of the palms of the hands and soles of the feet. The rash may appear as pimples that come to white tips on the face, chest, back, arms, legs, and head.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
2432 |
4. Check minimum number of eventsNone |
2432 |
5. Include endpoints |
2575 |
6. Filter based on genotype QC (FinnGen only) |
2461 |
Control definitions (FinnGen only)
Control exclude
L12_DISORDSKINAPPENDIX
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L60-L75
Name in latin
Aliae morbositates folliculares
Similar endpoints
↥List of similar endpoints to
Other follicular disorders
based on the number of shared cases.
Similar with more cases:
- Disorders of skin appendages
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 16746 | 8467 | 8174 |
| Only index persons | 15950 | 8223 | 7727 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.23 | 0.24 | 0.23 |
| Only index persons | 0.30 | 0.30 | 0.29 |
| Median age at first event (years) | |||
| Whole population | 40.29 | 37.83 | 42.88 |
| Only index persons | 39.98 | 37.64 | 42.46 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2461 | 1430 | 1031 |
| Unadjusted period prevalence (%) | 0.54 | 0.56 | 0.52 |
| Median age at first event (years) | 44.59 | 40.71 | 49.96 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint L12_FOLICULAROTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_FOLICULAROTH | 1.643 [1.39, 1.94] | < 0.001 |
| Birth year | 1.001 [0.99, 1.01] | 0.782 |
During the follow-up period (1.1.1998 — 31.12.2019), 383 out of 6150 females with L12_FOLICULAROTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_FOLICULAROTH | 1.583 [1.37, 1.83] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 732 out of 5914 males with L12_FOLICULAROTH died.
Mortality risk
Mortality risk for people of age
years, who have L12_FOLICULAROTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.235% | 0.313% |
| 5 | 1.093% | 1.937% |
| 10 | 2.95% | 4.503% |
| 15 | 5.676% | 8.454% |
| 20 | 10.286% | 14.633% |
Relationships between endpoints
↥Index endpoint: L12_FOLICULAROTH – Other follicular disorders
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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