No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
27786 |
4. Check minimum number of eventsNone |
27786 |
5. Include endpoints |
28649 |
6. Filter based on genotype QC (FinnGen only) |
27587 |
Control definitions (FinnGen only)
Control exclude
L12_DERMATITISECZEMA
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L20-L30
Name in latin
Alia dermatitis
Similar endpoints
↥List of similar endpoints to
Other and unspecified dermatitis
based on the number of shared cases.
Similar with more cases:
- Dermatitis and eczema
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 233278 | 129678 | 102310 |
| Only index persons | 210031 | 119849 | 90182 |
| Unadjusted period prevalence (%) | |||
| Whole population | 3.33 | 3.71 | 2.86 |
| Only index persons | 3.99 | 4.41 | 3.44 |
| Median age at first event (years) | |||
| Whole population | 51.09 | 50.93 | 51.33 |
| Only index persons | 51.25 | 51.02 | 51.55 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 27587 | 16626 | 10961 |
| Unadjusted period prevalence (%) | 6.12 | 6.53 | 5.50 |
| Median age at first event (years) | 54.90 | 52.30 | 58.84 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint L12_DERMATITISNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_DERMATITISNAS | 1.356 [1.24, 1.49] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.063 |
During the follow-up period (1.1.1998 — 31.12.2019), 14135 out of 104936 females with L12_DERMATITISNAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_DERMATITISNAS | 1.558 [1.42, 1.72] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 16177 out of 80635 males with L12_DERMATITISNAS died.
Mortality risk
Mortality risk for people of age
years, who have L12_DERMATITISNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.091% | 0.275% |
| 5 | 0.685% | 1.661% |
| 10 | 1.584% | 4.091% |
| 15 | 3.291% | 7.693% |
| 20 | 5.762% | 13.189% |
Relationships between endpoints
↥Index endpoint: L12_DERMATITISNAS – Other and unspecified dermatitis
GWS hits: 11
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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