No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
4351 |
4. Check minimum number of eventsNone |
4351 |
5. Include endpointsNone |
4351 |
6. Filter based on genotype QC (FinnGen only) |
4195 |
Control definitions (FinnGen only)
Control exclude
L12_DERMATITISECZEMA
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L30
Name in latin
Dermatitis infectiosa
Similar endpoints
↥List of similar endpoints to
Infective dermatitis
based on the number of shared cases.
Similar with more cases:
- Other and unspecified dermatitis
- Dermatitis and eczema
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 38784 | 18479 | 20130 |
| Only index persons | 35334 | 17298 | 18036 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.54 | 0.53 | 0.56 |
| Only index persons | 0.66 | 0.64 | 0.69 |
| Median age at first event (years) | |||
| Whole population | 52.86 | 51.94 | 53.63 |
| Only index persons | 52.28 | 51.57 | 52.96 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 4195 | 2154 | 2041 |
| Unadjusted period prevalence (%) | 0.93 | 0.85 | 1.03 |
| Median age at first event (years) | 54.94 | 51.19 | 58.90 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint L12_INFECT_DERM and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_INFECT_DERM | 1.469 [1.34, 1.61] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.014 |
During the follow-up period (1.1.1998 — 31.12.2019), 2882 out of 16388 females with L12_INFECT_DERM died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_INFECT_DERM | 1.857 [1.71, 2.02] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.05 |
During the follow-up period (1.1.1998 — 31.12.2019), 4766 out of 17856 males with L12_INFECT_DERM died.
Mortality risk
Mortality risk for people of age
years, who have L12_INFECT_DERM.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.141% | 0.336% |
| 5 | 0.862% | 2.178% |
| 10 | 1.864% | 6.076% |
| 15 | 3.692% | 11.038% |
| 20 | 6.611% | 18.34% |
Relationships between endpoints
↥Index endpoint: L12_INFECT_DERM – Infective dermatitis
GWS hits: 3
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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