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Ulcerative colitis

DOID EFO Endpoint Browser

K11_ULCER

ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — K51
  • Hospital discharge: ICD-9 — 556
  • Hospital discharge: ICD-8 — 5631|569
  • Hospital discharge: excluded ICD-9 — 5564A
  • Cause of death: ICD-10 — K51
  • Cause of death: ICD-9 — 556
  • Cause of death: ICD-8 — 5631|569
  • Cause of death: excluded ICD-9 — 5564A

2 out of 7 registries used, show all original rules.

10898

4. Check minimum number of events

None

10898

5. Include endpoints

None

10898

6. Filter based on genotype QC (FinnGen only)

10540

Control definitions (FinnGen only)

Control exclude K11_ENERCOLNONINF

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 K50-K52
Name in latin Colitis ulcerosa

Similar endpoints

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List of similar endpoints to Ulcerative colitis based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 10540 5479 5061
Unadjusted period prevalence (%) 2.34 2.15 2.54
Median age at first event (years) 40.90 38.11 43.92

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

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This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

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Index endpoint: K11_ULCER – Ulcerative colitis

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).