No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditions
|
210867 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
20842 |
6. Filter based on genotype QC (FinnGen only) |
20044 |
Control definitions (FinnGen only)
Control conditions
not BMI
>25
>25
Extra metadata
First used in FinnGen datafreeze
DF5
Similar endpoints
↥List of similar endpoints to
Heart failure and bmi 25plus
based on the number of shared cases.
Similar with more cases:
- Heart failure, strict
- Heart failure,strict
- Heart failure, not strict
- Other heart diseases
- Other heart diseases
Similar with less cases:
None
Case counts by codes
↥FinnGen case counts by registry codes:
No data for upset plot.
No data for upset table.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | - | - | - |
| Only index persons | - | - | - |
| Unadjusted period prevalence (%) | |||
| Whole population | - | - | - |
| Only index persons | - | - | - |
| Median age at first event (years) | |||
| Whole population | - | - | - |
| Only index persons | - | - | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 20044 | 6898 | 13146 |
| Unadjusted period prevalence (%) | 5.26 | 2.71 | 6.60 |
| Median age at first event (years) | 70.51 | 70.88 | 70.33 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint I9_HEARTFAIL_AND_OVERWEIGHT and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have I9_HEARTFAIL_AND_OVERWEIGHT.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: I9_HEARTFAIL_AND_OVERWEIGHT – Heart failure and bmi 25plus
GWS hits: 6
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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