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Operations 2 for CAVS

I9_CAVS_OPERATIONS2

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

  • I9_CAVS_DX
11440

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 I35.0, I35.2
  • Hospital discharge: ICD-9 4241[BC]
  • Cause of death: ICD-10 I35.0, I35.2
  • Cause of death: ICD-9 4241[BC]
  • Operations: NOMESCO codes ^FMD0[0-2]|^FMD15|^FMD96|^FME05|^FME[123467]0

3 out of 7 registries used, show all original rules.

11440

4. Check minimum number of events

None

11440

5. Include endpoints

None

11440

6. Filter based on genotype QC (FinnGen only)

11027

Control definitions (FinnGen only)

Control exclude I9_CAVS
Control conditions not I9_CAVS_DX

Extra metadata

First used in FinnGen datafreeze DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 11027 4131 6896
Unadjusted period prevalence (%) 2.77 1.62 3.46
Median age at first event (years) 72.86 74.35 71.96

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: I9_CAVS_OPERATIONS2 – Operations 2 for CAVS

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).