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Glaucoma secondary to other eye disorders

H7_GLAUCSECDISEASE

open-angle glaucoma: Chronic outflow obstruction of the eye's drainage canals that can lead to increased internal eye pressure and optic nerve damage.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H40.5
  • Hospital discharge: ICD-9 3655|3656A
  • Cause of death: ICD-10 H40.5
  • Cause of death: ICD-9 3655|3656A

2 out of 7 registries used, show all original rules.

1423

4. Check minimum number of events

None

1423

5. Include endpoints

None

1423

6. Filter based on genotype QC (FinnGen only)

1364

Control definitions (FinnGen only)

Control exclude H7_GLAUCOMA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H40
Name in latin Glaucoma [secundarium] post aliam morbositatem oculi

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 1364 628 736
Unadjusted period prevalence (%) 0.31 0.25 0.37
Median age at first event (years) 63.16 59.45 66.33

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: H7_GLAUCSECDISEASE – Glaucoma secondary to other eye disorders

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).