No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
453 |
6. Filter based on genotype QC (FinnGen only) |
430 |
Control definitions (FinnGen only)
Control exclude
H7_CHOROIDRETINA
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Other disorders of choroid
based on the number of shared cases.
Similar with more cases:
- Disorders of choroid and retina
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4103 | 2132 | 1941 |
| Only index persons | 3629 | 1908 | 1721 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.06 | 0.05 |
| Only index persons | 0.07 | 0.07 | 0.07 |
| Median age at first event (years) | |||
| Whole population | 63.92 | 67.31 | 60.08 |
| Only index persons | 62.24 | 65.65 | 58.46 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 430 | 215 | 215 |
| Unadjusted period prevalence (%) | 0.10 | 0.08 | 0.11 |
| Median age at first event (years) | 62.52 | 60.61 | 64.43 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint H7_CHOROIDOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CHOROIDOTH | 1.061 [0.92, 1.22] | 0.4 |
| Birth year | 0.998 [0.99, 1.01] | 0.675 |
During the follow-up period (1.1.1998 — 31.12.2019), 525 out of 1781 females with H7_CHOROIDOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CHOROIDOTH | 1.09 [0.93, 1.27] | 0.272 |
| Birth year | 0.988 [0.98, 1.0] | 0.013 |
During the follow-up period (1.1.1998 — 31.12.2019), 417 out of 1549 males with H7_CHOROIDOTH died.
Mortality risk
Mortality risk for people of age
years, who have H7_CHOROIDOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.112% | 0.209% |
| 5 | 0.689% | 1.294% |
| 10 | 1.593% | 3.192% |
| 15 | 3.182% | 5.938% |
| 20 | 5.824% | 10.166% |
Relationships between endpoints
↥Index endpoint: H7_CHOROIDOTH – Other disorders of choroid
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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