No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
101 |
4. Check minimum number of eventsNone |
101 |
5. Include endpointsNone |
101 |
6. Filter based on genotype QC (FinnGen only) |
98 |
Control definitions (FinnGen only)
Control exclude
H7_CHOROIDRETINA
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H31
Name in latin
Haemorrhagia chorioideae
Similar endpoints
↥List of similar endpoints to
Choroidal haemorrhage and rupture
based on the number of shared cases.
Similar with more cases:
- Other disorders of choroid
- Disorders of choroid and retina
- Bleeding
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1087 | 570 | 511 |
| Only index persons | 959 | 503 | 456 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.01 |
| Only index persons | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 70.48 | 75.66 | 64.66 |
| Only index persons | 69.40 | 75.24 | 62.96 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 98 | 39 | 59 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.03 |
| Median age at first event (years) | 65.19 | 63.06 | 66.59 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint H7_CHORHAEMORRHAGE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CHORHAEMORRHAGE | 1.035 [0.83, 1.28] | 0.757 |
| Birth year | 0.994 [0.99, 1.0] | 0.161 |
During the follow-up period (1.1.1998 — 31.12.2019), 194 out of 506 females with H7_CHORHAEMORRHAGE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CHORHAEMORRHAGE | 1.019 [0.79, 1.31] | 0.884 |
| Birth year | 0.992 [0.98, 1.0] | 0.089 |
During the follow-up period (1.1.1998 — 31.12.2019), 133 out of 419 males with H7_CHORHAEMORRHAGE died.
Mortality risk
Mortality risk for people of age
years, who have H7_CHORHAEMORRHAGE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.075% | 0.219% |
| 5 | 0.534% | 1.415% |
| 10 | 1.286% | 3.496% |
| 15 | 2.713% | 6.676% |
| 20 | 4.845% | 11.232% |
Relationships between endpoints
↥Index endpoint: H7_CHORHAEMORRHAGE – Choroidal haemorrhage and rupture
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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