No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
3427 |
4. Check minimum number of eventsNone |
3427 |
5. Include endpointsNone |
3427 |
6. Filter based on genotype QC (FinnGen only) |
3302 |
Control definitions (FinnGen only)
Control exclude
F5_NEUROTIC
Extra metadata
Level in the ICD hierarchy
5
First used in FinnGen datafreeze
DF6
Similar endpoints
↥List of similar endpoints to
Social phobias
based on the number of shared cases.
Similar with more cases:
- Phobic anxiety disorders
- Anxiety (asthma-related co-morbidities)
- All anxiety disorders
- Neurotic, stress-related and somatoform disorders
- Anxiety disorders
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 41492 | 22206 | 19196 |
| Only index persons | 40651 | 21951 | 18700 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.59 | 0.64 | 0.54 |
| Only index persons | 0.76 | 0.81 | 0.71 |
| Median age at first event (years) | |||
| Whole population | 25.26 | 23.50 | 27.28 |
| Only index persons | 25.06 | 23.36 | 27.05 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3302 | 2097 | 1205 |
| Unadjusted period prevalence (%) | 0.74 | 0.82 | 0.61 |
| Median age at first event (years) | 31.33 | 29.43 | 34.64 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint F5_SOCPHOB and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_SOCPHOB | 2.294 [2.0, 2.64] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.083 |
During the follow-up period (1.1.1998 — 31.12.2019), 511 out of 16949 females with F5_SOCPHOB died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_SOCPHOB | 2.387 [2.12, 2.68] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.145 |
During the follow-up period (1.1.1998 — 31.12.2019), 1053 out of 15465 males with F5_SOCPHOB died.
Mortality risk
Mortality risk for people of age
years, who have F5_SOCPHOB.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.233% | 0.475% |
| 5 | 1.426% | 3.474% |
| 10 | 3.534% | 8.488% |
| 15 | 6.524% | 15.719% |
| 20 | 10.601% | 24.867% |
Relationships between endpoints
↥Index endpoint: F5_SOCPHOB – Social phobias
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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