This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
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This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
D3_CVID_TCELL
obsolete_common variable immunodeficiency: ['A hypogammaglobulinemia that is results in insufficient production of antibodies needed to respond to exposure of pathogens and is characterized by low Ig levels with phenotypically normal B cells that can proliferate but do not develop into Ig-producing cells. Patients with common variable immunodeficiency have marked reduction in serum levels of both immunoglobulin G (IgG) and immunoglobulin A (IgA); about half of these patients also have reduced immunoglobulin M (IgM).', 'A primary immunodeficiency characterized by low levels or absence of all the immunoglobulin classes and lack of B-lymphocytes or plasma cells. It results in recurrent bacterial infections. Complications include autoimmune phenomena and cancer development.', 'Heterogeneous group of immunodeficiency syndromes characterized by hypogammaglobulinemia of most isotypes, variable B-cell defects, and the presence of recurrent bacterial infections.']
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
43 |
4. Check minimum number of eventsNone |
43 |
5. Include endpointsNone |
43 |
6. Filter based on genotype QC (FinnGen only) |
42 |
Control definitions (FinnGen only)
Extra metadata
List of similar endpoints to Common variable immunodeficiency with predominant abnormalities of T-cell numbers and function based on the number of shared cases.
Similar with more cases:
Similar with less cases:
None
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 204 | 98 | 102 |
Only index persons | 165 | 86 | 79 |
Unadjusted period prevalence (%) | |||
Whole population | 0.00 | 0.00 | 0.00 |
Only index persons | 0.00 | 0.00 | 0.00 |
Median age at first event (years) | |||
Whole population | 60.05 | 57.52 | 61.99 |
Only index persons | 57.77 | 56.84 | 58.79 |
All | Female | Male | |
---|---|---|---|
Number of individuals | 42 | 27 | 15 |
Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
Median age at first event (years) | 60.62 | 56.12 | 68.73 |
Not a core endpoint, no data to show.
Association between endpoint D3_CVID_TCELL and mortality.
Mortality risk for people of age
years, who have D3_CVID_TCELL.N-year risk | Females | Males |
---|---|---|
1 | No data | No data |
5 | No data | No data |
10 | No data | No data |
15 | No data | No data |
20 | No data | No data |
Index endpoint: D3_CVID_TCELL – Common variable immunodeficiency with predominant abnormalities of T-cell numbers and function
GWS hits: -