No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
17804 |
6. Filter based on genotype QC (FinnGen only) |
17111 |
Control definitions (FinnGen only)
Control exclude
D3_NUTRIANAEMIA
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Iron deficiency anaemia
based on the number of shared cases.
Similar with more cases:
- Nutritional anaemias
- Anaemias
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No data for upset plot.
No data for upset table.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 173455 | 110612 | 61069 |
| Only index persons | 140546 | 93090 | 47456 |
| Unadjusted period prevalence (%) | |||
| Whole population | 2.64 | 3.17 | 1.71 |
| Only index persons | 2.88 | 3.42 | 1.81 |
| Median age at first event (years) | |||
| Whole population | 64.45 | 62.41 | 68.13 |
| Only index persons | 60.72 | 57.24 | 67.55 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 17111 | 10366 | 6745 |
| Unadjusted period prevalence (%) | 3.80 | 4.07 | 3.39 |
| Median age at first event (years) | 59.25 | 52.30 | 69.94 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint D3_ANAEMIA_IRONDEF and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_ANAEMIA_IRONDEF | 2.094 [1.89, 2.32] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.288 |
During the follow-up period (1.1.1998 — 31.12.2019), 24740 out of 70954 females with D3_ANAEMIA_IRONDEF died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_ANAEMIA_IRONDEF | 2.622 [2.32, 2.96] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.017 |
During the follow-up period (1.1.1998 — 31.12.2019), 19220 out of 41536 males with D3_ANAEMIA_IRONDEF died.
Mortality risk
Mortality risk for people of age
years, who have D3_ANAEMIA_IRONDEF.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.195% | 0.449% |
| 5 | 0.952% | 2.716% |
| 10 | 2.68% | 6.83% |
| 15 | 5.451% | 13.267% |
| 20 | 9.654% | 22.809% |
Relationships between endpoints
↥Index endpoint: D3_ANAEMIA_IRONDEF – Iron deficiency anaemia
GWS hits: 6
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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