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Early onset COPD

Endpoint Browser

COPD_EARLY_EXMORE

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Pre-conditions: EVENT_AGE<65

Registry filters:

  • Hospital discharge: ICD-10 — J44
  • Hospital discharge: ICD-9 — 4912
  • Hospital discharge: ICD-8 — 49104
  • Cause of death: ICD-10 — J44
  • Cause of death: ICD-9 — 4912
  • Cause of death: ICD-8 — 49104

2 out of 7 registries used, show all original rules.

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4. Check minimum number of events

None

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5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude COPD_EARLYANDLATER, COPD_EXCL

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 J40-J47
Name in latin Alii morbi obstructivi chronici pulmonum

Case counts by codes

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FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 8266 3066 5200
Unadjusted period prevalence (%) 2.09 1.20 2.61
Median age at first event (years) 57.20 55.70 58.09

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

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This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

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Index endpoint: COPD_EARLY_EXMORE – Early onset COPD

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).