No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
350 |
4. Check minimum number of eventsNone |
350 |
5. Include endpointsNone |
350 |
6. Filter based on genotype QC (FinnGen only) |
336 |
Control definitions (FinnGen only)
Control exclude
RHEUMA_CHRYSTAL
Extra metadata
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M11
Name in latin
Aliae chondrocalcinoses
Similar endpoints
↥List of similar endpoints to
Other chondrocalcinosis
based on the number of shared cases.
Similar with more cases:
- Other crystal arthropathies
- Crystal arthropathies, rheuma endpoint
- Polyarthropathies
- Finngen Rheumatological endpoints
- Arthropathies
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2560 | 1394 | 1157 |
| Only index persons | 2391 | 1295 | 1096 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | 0.03 |
| Only index persons | 0.04 | 0.05 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 75.78 | 78.31 | 72.85 |
| Only index persons | 75.84 | 78.30 | 72.92 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 336 | 158 | 178 |
| Unadjusted period prevalence (%) | 0.08 | 0.06 | 0.09 |
| Median age at first event (years) | 73.94 | 73.19 | 74.61 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint CHONDRO_OTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CHONDRO_OTH | 1.335 [1.09, 1.63] | 0.004 |
| Birth year | 0.997 [0.99, 1.01] | 0.533 |
During the follow-up period (1.1.1998 — 31.12.2019), 447 out of 1101 females with CHONDRO_OTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CHONDRO_OTH | 1.598 [1.24, 2.05] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 335 out of 887 males with CHONDRO_OTH died.
Mortality risk
Mortality risk for people of age
years, who have CHONDRO_OTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.165% | 0.255% |
| 5 | 0.921% | 1.688% |
| 10 | 2.104% | 4.222% |
| 15 | 4.053% | 8.131% |
| 20 | 7.215% | 13.94% |
Relationships between endpoints
↥Index endpoint: CHONDRO_OTH – Other chondrocalcinosis
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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