No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
1258 |
6. Filter based on genotype QC (FinnGen only) |
1197 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Small intestine
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Small intestine
- Benign neoplasm of other and ill-defined parts of digestive system
- Benign neoplasm of other and ill-defined parts of digestive system
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No data for upset plot.
No data for upset table.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7837 | 4216 | 3574 |
| Only index persons | 6967 | 3829 | 3138 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.11 | 0.12 | 0.10 |
| Only index persons | 0.13 | 0.14 | 0.12 |
| Median age at first event (years) | |||
| Whole population | 64.82 | 64.43 | 65.25 |
| Only index persons | 64.27 | 63.88 | 64.75 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1197 | 684 | 513 |
| Unadjusted period prevalence (%) | 0.26 | 0.27 | 0.26 |
| Median age at first event (years) | 63.17 | 61.34 | 65.61 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_SMALL_INTESTINE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_SMALL_INTESTINE | 1.491 [1.32, 1.68] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.56 |
During the follow-up period (1.1.1998 — 31.12.2019), 874 out of 3407 females with CD2_BENIGN_SMALL_INTESTINE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_SMALL_INTESTINE | 1.557 [1.36, 1.78] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.012 |
During the follow-up period (1.1.1998 — 31.12.2019), 982 out of 2911 males with CD2_BENIGN_SMALL_INTESTINE died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_SMALL_INTESTINE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.111% | 0.27% |
| 5 | 0.822% | 1.908% |
| 10 | 2.147% | 4.633% |
| 15 | 4.295% | 8.976% |
| 20 | 7.835% | 15.246% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_SMALL_INTESTINE – Benign neoplasm: Small intestine
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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