No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
775 |
4. Check minimum number of eventsNone |
775 |
5. Include endpointsNone |
775 |
6. Filter based on genotype QC (FinnGen only) |
748 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D13
Name in latin
Neoplasma benignum duodeni
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Duodenum
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Duodenum
- Benign neoplasm: Small intestine
- Benign neoplasm: Small intestine
- Benign neoplasm of other and ill-defined parts of digestive system
- Benign neoplasm of other and ill-defined parts of digestive system
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4501 | 2253 | 2225 |
| Only index persons | 4114 | 2085 | 2029 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.06 | 0.06 |
| Only index persons | 0.08 | 0.08 | 0.08 |
| Median age at first event (years) | |||
| Whole population | 66.66 | 66.94 | 66.36 |
| Only index persons | 66.34 | 66.64 | 66.04 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 748 | 402 | 346 |
| Unadjusted period prevalence (%) | 0.17 | 0.16 | 0.17 |
| Median age at first event (years) | 66.42 | 65.48 | 67.51 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_DUODENUM and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_DUODENUM | 1.736 [1.49, 2.02] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.143 |
During the follow-up period (1.1.1998 — 31.12.2019), 518 out of 1933 females with CD2_BENIGN_DUODENUM died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_DUODENUM | 2.001 [1.7, 2.36] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 669 out of 1893 males with CD2_BENIGN_DUODENUM died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_DUODENUM.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.129% | 0.405% |
| 5 | 0.957% | 2.134% |
| 10 | 2.273% | 5.405% |
| 15 | 4.66% | 10.356% |
| 20 | 8.151% | 16.828% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_DUODENUM – Benign neoplasm: Duodenum
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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