salivary gland neoplasm: ['Tumors of the SALIVARY GLANDS.']
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
3104 |
4. Check minimum number of eventsNone |
3104 |
5. Include endpoints |
3462 |
6. Filter based on genotype QC (FinnGen only) |
3353 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10-D36
Name in latin
Neoplasmata benigna glandularum salivariarum majorum
Similar endpoints
↥List of similar endpoints to
Benign neoplasm of major salivary glands
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm of major salivary glands
- Benign neoplasms
- Benign neoplasms
- Neoplasms
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 24561 | 12823 | 11557 |
| Only index persons | 21875 | 11713 | 10162 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.35 | 0.37 | 0.32 |
| Only index persons | 0.41 | 0.43 | 0.39 |
| Median age at first event (years) | |||
| Whole population | 58.45 | 58.19 | 58.72 |
| Only index persons | 57.54 | 57.27 | 57.85 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3353 | 1712 | 1641 |
| Unadjusted period prevalence (%) | 0.75 | 0.67 | 0.82 |
| Median age at first event (years) | 58.22 | 55.50 | 61.05 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_SALIVARY and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_SALIVARY | 1.266 [1.15, 1.4] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.298 |
During the follow-up period (1.1.1998 — 31.12.2019), 1813 out of 9078 females with CD2_BENIGN_SALIVARY died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_SALIVARY | 1.404 [1.27, 1.55] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.016 |
During the follow-up period (1.1.1998 — 31.12.2019), 2119 out of 8404 males with CD2_BENIGN_SALIVARY died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_SALIVARY.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.116% | 0.207% |
| 5 | 0.742% | 1.619% |
| 10 | 1.878% | 4.099% |
| 15 | 3.653% | 7.984% |
| 20 | 6.59% | 13.355% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_SALIVARY – Benign neoplasm of major salivary glands
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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