rectum cancer: A primary or metastatic malignant neoplasm that affects the rectum. Representative examples include carcinoma, lymphoma, and sarcoma.
Benign neoplasm: Rectum, anus and anal canal
DOID EFO Endpoint Browser PheWeb
CD2_BENIGN_RECTUM_ANAL
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
7152 |
6. Filter based on genotype QC (FinnGen only) |
6913 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Similar endpoints
↥List of similar endpoints to Benign neoplasm: Rectum, anus and anal canal based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Rectum, anus and anal canal
- Benign neoplasm of colon, rectum, anus and anal canal
- Benign neoplasm of colon, rectum, anus and anal canal
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 46435 | 23043 | 23086 |
Only index persons | 41450 | 21048 | 20402 |
Unadjusted period prevalence (%) | |||
Whole population | 0.65 | 0.66 | 0.65 |
Only index persons | 0.78 | 0.77 | 0.78 |
Median age at first event (years) | |||
Whole population | 65.74 | 65.69 | 65.75 |
Only index persons | 65.19 | 65.09 | 65.30 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 6913 | 3287 | 3626 |
Unadjusted period prevalence (%) | 1.57 | 1.29 | 1.82 |
Median age at first event (years) | 65.16 | 63.46 | 66.69 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_RECTUM_ANAL and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
CD2_BENIGN_RECTUM_ANAL | 1.132 [1.04, 1.23] | 0.005 |
Birth year | 0.996 [0.99, 1.0] | 0.264 |
During the follow-up period (1.1.1998 — 31.12.2019), 3757 out of 17553 females with CD2_BENIGN_RECTUM_ANAL died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
CD2_BENIGN_RECTUM_ANAL | 1.235 [1.13, 1.35] | < 0.001 |
Birth year | 0.987 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 4969 out of 17500 males with CD2_BENIGN_RECTUM_ANAL died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_RECTUM_ANAL.N-year risk | Females | Males |
---|---|---|
1 | 0.127% | 0.226% |
5 | 0.703% | 1.476% |
10 | 1.868% | 3.671% |
15 | 3.512% | 6.876% |
20 | 5.84% | 11.146% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_RECTUM_ANAL – Benign neoplasm: Rectum, anus and anal canal
GWS hits: 5