No definition available.
Benign neoplasm of colon, rectum, anus and anal canal
CD2_BENIGN_COLORECANI
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
25653 |
4. Check minimum number of eventsNone |
25653 |
5. Include endpoints |
26123 |
6. Filter based on genotype QC (FinnGen only) |
25190 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10-D36
Name in latin
Neoplasma benignum intestini crassi
Similar endpoints
↥List of similar endpoints to
Benign neoplasm of colon, rectum, anus and anal canal
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm of colon, rectum, anus and anal canal
- Benign neoplasms
- Benign neoplasms
- Neoplasms
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 166694 | 83081 | 82674 |
| Only index persons | 152318 | 77591 | 74727 |
| Unadjusted period prevalence (%) | |||
| Whole population | 2.34 | 2.38 | 2.31 |
| Only index persons | 2.85 | 2.85 | 2.85 |
| Median age at first event (years) | |||
| Whole population | 66.20 | 66.21 | 66.18 |
| Only index persons | 65.73 | 65.73 | 65.74 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 25190 | 12388 | 12802 |
| Unadjusted period prevalence (%) | 5.66 | 4.87 | 6.43 |
| Median age at first event (years) | 65.49 | 64.09 | 66.84 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_COLORECANI and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_COLORECANI | 1.236 [1.14, 1.34] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.223 |
During the follow-up period (1.1.1998 — 31.12.2019), 14200 out of 66651 females with CD2_BENIGN_COLORECANI died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_COLORECANI | 1.328 [1.21, 1.45] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 19311 out of 66453 males with CD2_BENIGN_COLORECANI died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_COLORECANI.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.104% | 0.227% |
| 5 | 0.658% | 1.578% |
| 10 | 1.776% | 3.844% |
| 15 | 3.638% | 7.17% |
| 20 | 6.368% | 12.114% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_COLORECANI – Benign neoplasm of colon, rectum, anus and anal canal
GWS hits: 19
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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