No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
8869 |
4. Check minimum number of eventsNone |
8869 |
5. Include endpointsNone |
8869 |
6. Filter based on genotype QC (FinnGen only) |
8548 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D12
Name in latin
Neoplasma benignum coli non specificati
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Colon, unspecified
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Colon, unspecified
- Benign neoplasm: Colon
- Benign neoplasm: Colon
- Benign neoplasm of colon, rectum, anus and anal canal
- Benign neoplasm of colon, rectum, anus and anal canal
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 61104 | 29072 | 31664 |
| Only index persons | 55444 | 27081 | 28363 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.86 | 0.83 | 0.88 |
| Only index persons | 1.04 | 1.00 | 1.08 |
| Median age at first event (years) | |||
| Whole population | 66.84 | 66.81 | 66.86 |
| Only index persons | 66.31 | 66.21 | 66.41 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 8548 | 3907 | 4641 |
| Unadjusted period prevalence (%) | 1.97 | 1.53 | 2.33 |
| Median age at first event (years) | 66.01 | 64.54 | 67.24 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_COLON_NOS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_COLON_NOS | 1.247 [1.15, 1.35] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.173 |
During the follow-up period (1.1.1998 — 31.12.2019), 5385 out of 24321 females with CD2_BENIGN_COLON_NOS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_COLON_NOS | 1.32 [1.21, 1.44] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.007 |
During the follow-up period (1.1.1998 — 31.12.2019), 8211 out of 26460 males with CD2_BENIGN_COLON_NOS died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_COLON_NOS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.086% | 0.228% |
| 5 | 0.655% | 1.469% |
| 10 | 1.689% | 3.79% |
| 15 | 3.101% | 7.273% |
| 20 | 5.603% | 12.508% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_COLON_NOS – Benign neoplasm: Colon, unspecified
GWS hits: 4
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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